gdf-5 growth factor Search Results


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Qiagen gdf5 (mm_gdf5_1_sg)
( A ) qRT-PCR expression levels of ligands BMP10 and <t>GDF5,</t> and receptors ALK1, Endoglin and ALK5 in whole PanNET tumors from RIP1-TAg2 wildtype, and Gdf2 knockout mice at 12 weeks. ( B – D ) Total PanNET tumor volume (B), number of tumors (C) and number of angiogenic islets (D) from RIP1-TAg2 mice at 12 weeks. ( E – J ) Expression correlation of GDF2 and BMP10 against ACVRL1, ENG and an endothelial metagene (CD34, CDH5, PECAM1), (E–I) , and of GDF2 against BMP10 (J) from a human dataset of pancreatic neuroendocrine tumors and metastases ( K – N ) Expression correlation of Gdf2 against Acvrl1 , Eng , an endothelial metagene ( CD34 , CDH5 , PECAM1 ), and Bmp10 (K-N) from a mouse dataset of pancreatic neuroendocrine RIP1-TAg2 islets, tumors and metastases Data are mean ± SEM. * P < 0.05; ** P < 0.01; *** P < 0.001 vs. Wildtype with Student's t-test .
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Beyotime gdf-5 growth factor
( A ) qRT-PCR expression levels of ligands BMP10 and <t>GDF5,</t> and receptors ALK1, Endoglin and ALK5 in whole PanNET tumors from RIP1-TAg2 wildtype, and Gdf2 knockout mice at 12 weeks. ( B – D ) Total PanNET tumor volume (B), number of tumors (C) and number of angiogenic islets (D) from RIP1-TAg2 mice at 12 weeks. ( E – J ) Expression correlation of GDF2 and BMP10 against ACVRL1, ENG and an endothelial metagene (CD34, CDH5, PECAM1), (E–I) , and of GDF2 against BMP10 (J) from a human dataset of pancreatic neuroendocrine tumors and metastases ( K – N ) Expression correlation of Gdf2 against Acvrl1 , Eng , an endothelial metagene ( CD34 , CDH5 , PECAM1 ), and Bmp10 (K-N) from a mouse dataset of pancreatic neuroendocrine RIP1-TAg2 islets, tumors and metastases Data are mean ± SEM. * P < 0.05; ** P < 0.01; *** P < 0.001 vs. Wildtype with Student's t-test .
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STEMCELL Technologies Inc gdf5 growth factor
( A ) qRT-PCR expression levels of ligands BMP10 and <t>GDF5,</t> and receptors ALK1, Endoglin and ALK5 in whole PanNET tumors from RIP1-TAg2 wildtype, and Gdf2 knockout mice at 12 weeks. ( B – D ) Total PanNET tumor volume (B), number of tumors (C) and number of angiogenic islets (D) from RIP1-TAg2 mice at 12 weeks. ( E – J ) Expression correlation of GDF2 and BMP10 against ACVRL1, ENG and an endothelial metagene (CD34, CDH5, PECAM1), (E–I) , and of GDF2 against BMP10 (J) from a human dataset of pancreatic neuroendocrine tumors and metastases ( K – N ) Expression correlation of Gdf2 against Acvrl1 , Eng , an endothelial metagene ( CD34 , CDH5 , PECAM1 ), and Bmp10 (K-N) from a mouse dataset of pancreatic neuroendocrine RIP1-TAg2 islets, tumors and metastases Data are mean ± SEM. * P < 0.05; ** P < 0.01; *** P < 0.001 vs. Wildtype with Student's t-test .
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Scil Technology GmbH gdf 5
( A ) qRT-PCR expression levels of ligands BMP10 and <t>GDF5,</t> and receptors ALK1, Endoglin and ALK5 in whole PanNET tumors from RIP1-TAg2 wildtype, and Gdf2 knockout mice at 12 weeks. ( B – D ) Total PanNET tumor volume (B), number of tumors (C) and number of angiogenic islets (D) from RIP1-TAg2 mice at 12 weeks. ( E – J ) Expression correlation of GDF2 and BMP10 against ACVRL1, ENG and an endothelial metagene (CD34, CDH5, PECAM1), (E–I) , and of GDF2 against BMP10 (J) from a human dataset of pancreatic neuroendocrine tumors and metastases ( K – N ) Expression correlation of Gdf2 against Acvrl1 , Eng , an endothelial metagene ( CD34 , CDH5 , PECAM1 ), and Bmp10 (K-N) from a mouse dataset of pancreatic neuroendocrine RIP1-TAg2 islets, tumors and metastases Data are mean ± SEM. * P < 0.05; ** P < 0.01; *** P < 0.001 vs. Wildtype with Student's t-test .
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( A ) qRT-PCR expression levels of ligands BMP10 and <t>GDF5,</t> and receptors ALK1, Endoglin and ALK5 in whole PanNET tumors from RIP1-TAg2 wildtype, and Gdf2 knockout mice at 12 weeks. ( B – D ) Total PanNET tumor volume (B), number of tumors (C) and number of angiogenic islets (D) from RIP1-TAg2 mice at 12 weeks. ( E – J ) Expression correlation of GDF2 and BMP10 against ACVRL1, ENG and an endothelial metagene (CD34, CDH5, PECAM1), (E–I) , and of GDF2 against BMP10 (J) from a human dataset of pancreatic neuroendocrine tumors and metastases ( K – N ) Expression correlation of Gdf2 against Acvrl1 , Eng , an endothelial metagene ( CD34 , CDH5 , PECAM1 ), and Bmp10 (K-N) from a mouse dataset of pancreatic neuroendocrine RIP1-TAg2 islets, tumors and metastases Data are mean ± SEM. * P < 0.05; ** P < 0.01; *** P < 0.001 vs. Wildtype with Student's t-test .
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MBL Life science recombinant human gdf-5
( A ) qRT-PCR expression levels of ligands BMP10 and <t>GDF5,</t> and receptors ALK1, Endoglin and ALK5 in whole PanNET tumors from RIP1-TAg2 wildtype, and Gdf2 knockout mice at 12 weeks. ( B – D ) Total PanNET tumor volume (B), number of tumors (C) and number of angiogenic islets (D) from RIP1-TAg2 mice at 12 weeks. ( E – J ) Expression correlation of GDF2 and BMP10 against ACVRL1, ENG and an endothelial metagene (CD34, CDH5, PECAM1), (E–I) , and of GDF2 against BMP10 (J) from a human dataset of pancreatic neuroendocrine tumors and metastases ( K – N ) Expression correlation of Gdf2 against Acvrl1 , Eng , an endothelial metagene ( CD34 , CDH5 , PECAM1 ), and Bmp10 (K-N) from a mouse dataset of pancreatic neuroendocrine RIP1-TAg2 islets, tumors and metastases Data are mean ± SEM. * P < 0.05; ** P < 0.01; *** P < 0.001 vs. Wildtype with Student's t-test .
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Bio-Path Inc growth differentiation factor 5 (gdf5
( A ) qRT-PCR expression levels of ligands BMP10 and <t>GDF5,</t> and receptors ALK1, Endoglin and ALK5 in whole PanNET tumors from RIP1-TAg2 wildtype, and Gdf2 knockout mice at 12 weeks. ( B – D ) Total PanNET tumor volume (B), number of tumors (C) and number of angiogenic islets (D) from RIP1-TAg2 mice at 12 weeks. ( E – J ) Expression correlation of GDF2 and BMP10 against ACVRL1, ENG and an endothelial metagene (CD34, CDH5, PECAM1), (E–I) , and of GDF2 against BMP10 (J) from a human dataset of pancreatic neuroendocrine tumors and metastases ( K – N ) Expression correlation of Gdf2 against Acvrl1 , Eng , an endothelial metagene ( CD34 , CDH5 , PECAM1 ), and Bmp10 (K-N) from a mouse dataset of pancreatic neuroendocrine RIP1-TAg2 islets, tumors and metastases Data are mean ± SEM. * P < 0.05; ** P < 0.01; *** P < 0.001 vs. Wildtype with Student's t-test .
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Verum Diagnostica GmbH gdf-5 growth factor
( A ) qRT-PCR expression levels of ligands BMP10 and <t>GDF5,</t> and receptors ALK1, Endoglin and ALK5 in whole PanNET tumors from RIP1-TAg2 wildtype, and Gdf2 knockout mice at 12 weeks. ( B – D ) Total PanNET tumor volume (B), number of tumors (C) and number of angiogenic islets (D) from RIP1-TAg2 mice at 12 weeks. ( E – J ) Expression correlation of GDF2 and BMP10 against ACVRL1, ENG and an endothelial metagene (CD34, CDH5, PECAM1), (E–I) , and of GDF2 against BMP10 (J) from a human dataset of pancreatic neuroendocrine tumors and metastases ( K – N ) Expression correlation of Gdf2 against Acvrl1 , Eng , an endothelial metagene ( CD34 , CDH5 , PECAM1 ), and Bmp10 (K-N) from a mouse dataset of pancreatic neuroendocrine RIP1-TAg2 islets, tumors and metastases Data are mean ± SEM. * P < 0.05; ** P < 0.01; *** P < 0.001 vs. Wildtype with Student's t-test .
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Image Search Results


( A ) qRT-PCR expression levels of ligands BMP10 and GDF5, and receptors ALK1, Endoglin and ALK5 in whole PanNET tumors from RIP1-TAg2 wildtype, and Gdf2 knockout mice at 12 weeks. ( B – D ) Total PanNET tumor volume (B), number of tumors (C) and number of angiogenic islets (D) from RIP1-TAg2 mice at 12 weeks. ( E – J ) Expression correlation of GDF2 and BMP10 against ACVRL1, ENG and an endothelial metagene (CD34, CDH5, PECAM1), (E–I) , and of GDF2 against BMP10 (J) from a human dataset of pancreatic neuroendocrine tumors and metastases ( K – N ) Expression correlation of Gdf2 against Acvrl1 , Eng , an endothelial metagene ( CD34 , CDH5 , PECAM1 ), and Bmp10 (K-N) from a mouse dataset of pancreatic neuroendocrine RIP1-TAg2 islets, tumors and metastases Data are mean ± SEM. * P < 0.05; ** P < 0.01; *** P < 0.001 vs. Wildtype with Student's t-test .

Journal: Oncotarget

Article Title: Compound genetically engineered mouse models of cancer reveal dual targeting of ALK1 and endoglin as a synergistic opportunity to impinge on angiogenic TGF-β signaling

doi: 10.18632/oncotarget.12604

Figure Lengend Snippet: ( A ) qRT-PCR expression levels of ligands BMP10 and GDF5, and receptors ALK1, Endoglin and ALK5 in whole PanNET tumors from RIP1-TAg2 wildtype, and Gdf2 knockout mice at 12 weeks. ( B – D ) Total PanNET tumor volume (B), number of tumors (C) and number of angiogenic islets (D) from RIP1-TAg2 mice at 12 weeks. ( E – J ) Expression correlation of GDF2 and BMP10 against ACVRL1, ENG and an endothelial metagene (CD34, CDH5, PECAM1), (E–I) , and of GDF2 against BMP10 (J) from a human dataset of pancreatic neuroendocrine tumors and metastases ( K – N ) Expression correlation of Gdf2 against Acvrl1 , Eng , an endothelial metagene ( CD34 , CDH5 , PECAM1 ), and Bmp10 (K-N) from a mouse dataset of pancreatic neuroendocrine RIP1-TAg2 islets, tumors and metastases Data are mean ± SEM. * P < 0.05; ** P < 0.01; *** P < 0.001 vs. Wildtype with Student's t-test .

Article Snippet: The following pre-validated primers were obtained from Qiagen: RPL19 (Mm_Rpl19_2_SG), BMP10 (Mm_BMP10_1_SG), GDF5 (Mm_Gdf5_1_SG), HEY1 (Mm_Hey1_1_SG), VEGFR1 (Mm_Flt1_1_SG), and VEGFR2 (Mm_Kdr_1_SG).

Techniques: Quantitative RT-PCR, Expressing, Knock-Out